Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21393370 | 0.79 | TRIM24 (0.38) | TRIM24TRIM33ATM | |
| SCHEMBL17821042 | 0.70 | TRIM24 (0.50) | TRIM24TRIM33ATMALDH1A1GAA | |
| SCHEMBL21393349 | 0.67 | IDH1 (0.37) | ALDH1A1GAA | |
| SCHEMBL21393358 | 0.64 | SMN1; SMN2 (0.31) | — | |
| SCHEMBL8604090 | 0.61 | CA12 (0.52) | ALDH1A1L3MBTL1 | |
| SCHEMBL29611953 | 0.61 | CA12 (0.52) | ALDH1A1L3MBTL1 | |
| SCHEMBL14993028 | 0.60 | — | — | |
| SCHEMBL27589630 | 0.60 | — | — | |
| SCHEMBL536875 | 0.59 | — | — | |
| SCHEMBL6366952 | 0.59 | SMN1; SMN2 (0.38) | ALDH1A1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019182925-A1 | OXADIAZOLE TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2019-09-26 | — | — | WO | disclosed |