Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21393695 | 0.64 | TRIM24 (0.38) | — | |
| SCHEMBL8604090 | 0.59 | CA12 (0.52) | SMN1; SMN2 | |
| SCHEMBL29611953 | 0.59 | CA12 (0.52) | SMN1; SMN2 | |
| SCHEMBL11529888 | 0.57 | NPC1 (0.38) | SMN1; SMN2 | |
| SCHEMBL27589630 | 0.57 | — | — | |
| SCHEMBL14993028 | 0.57 | — | — | |
| SCHEMBL21393694 | 0.57 | CA12 (0.32) | SMN1; SMN2 | |
| SCHEMBL21393349 | 0.57 | IDH1 (0.37) | — | |
| SCHEMBL31666972 | 0.56 | SMN1; SMN2 (0.36) | SMN1; SMN2 | |
| SCHEMBL3420520 | 0.56 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019182925-A1 | OXADIAZOLE TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2019-09-26 | — | — | WO | disclosed |