Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335081 | 0.65 | KDM4E (0.60) | KDM4EALDH1A1KMT2AHSD17B10L3MBTL1 | |
| SCHEMBL17290828 | 0.63 | KDM4E (0.44) | KDM4EALDH1A1KMT2AHSD17B10L3MBTL1 | |
| SCHEMBL14269336 | 0.62 | KDM4E (0.43) | KDM4EALDH1A1KMT2AHSD17B10L3MBTL1 | |
| SCHEMBL8261357 | 0.62 | L3MBTL1 (0.56) | KDM4EALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL15559856 | 0.62 | KDM4E (0.43) | KDM4EALDH1A1KMT2AHSD17B10L3MBTL1 | |
| SCHEMBL21393820 | 0.60 | GAA (0.30) | — | |
| SCHEMBL21393786 | 0.59 | POLB (0.31) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL21393598 | 0.59 | PDE7A (0.30) | — | |
| SCHEMBL23123196 | 0.59 | KMT2A (0.46) | KDM4EALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL21393891 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019182925-A1 | OXADIAZOLE TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2019-09-26 | — | — | WO | disclosed |