Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21393820 | 0.88 | GAA (0.30) | — | |
| SCHEMBL21393598 | 0.86 | PDE7A (0.30) | — | |
| SCHEMBL21393792 | 0.81 | KDM4E (0.36) | POLBKDM4EALDH1A1 | |
| SCHEMBL21393793 | 0.72 | — | — | |
| SCHEMBL21393791 | 0.63 | GAA (0.30) | — | |
| SCHEMBL21393891 | 0.62 | — | — | |
| SCHEMBL21393696 | 0.59 | KDM4E (0.36) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL21393828 | 0.59 | — | — | |
| SCHEMBL22135199 | 0.58 | ALDH1A1 (0.35) | POLBKDM4EALDH1A1TP53MAPT | |
| SCHEMBL4640488 | 0.57 | TP53 (0.36) | POLBKDM4EALDH1A1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019182925-A1 | OXADIAZOLE TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2019-09-26 | — | — | WO | disclosed |