Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.30 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22210022 | 0.81 | KDM5A (0.34) | PLAU | |
| SCHEMBL21393412 | 0.81 | TYK2 (0.35) | ALDH1A1THRB | |
| SCHEMBL6628045 | 0.75 | CSNK1A1 (0.38) | CSNK1A1CSNK1DCLK2CSNK1G1ALDH1A1 | |
| SCHEMBL31662998 | 0.75 | CSNK1A1 (0.38) | CSNK1A1CSNK1DCLK2CSNK1G1ALDH1A1 | |
| SCHEMBL21393782 | 0.73 | CYP1A2 (0.32) | PLAUALDH1A1CYP2C19 | |
| SCHEMBL25932246 | 0.72 | CSNK1A1 (0.36) | CSNK1A1CSNK1DCLK2CSNK1G1ALDH1A1 | |
| SCHEMBL17692459 | 0.72 | SMN1; SMN2 (0.37) | CSNK1A1CSNK1DCLK2CSNK1G1ALDH1A1 | |
| SCHEMBL28700162 | 0.72 | NAPRT (0.37) | CSNK1A1CSNK1DCLK2CSNK1G1ALDH1A1 | |
| SCHEMBL20203156 | 0.69 | CCR1 (0.32) | PLAUCCR1CCR5CCR8NOS3 | |
| SCHEMBL6578250 | 0.67 | KDM4E (0.43) | ALDH1A1CCR1CCR5CCR8SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019182925-A1 | OXADIAZOLE TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2019-09-26 | — | — | WO | disclosed |