Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21393825 | 0.73 | CSNK1A1 (0.33) | CYP2C19PLAUALDH1A1 | |
| SCHEMBL31662998 | 0.67 | CSNK1A1 (0.38) | CYP2C19ALDH1A1 | |
| SCHEMBL6628045 | 0.67 | CSNK1A1 (0.38) | CYP2C19ALDH1A1 | |
| SCHEMBL25932246 | 0.64 | CSNK1A1 (0.36) | CYP2C19ALDH1A1 | |
| SCHEMBL28700162 | 0.64 | NAPRT (0.37) | CYP2C19ALDH1A1 | |
| SCHEMBL17692459 | 0.64 | SMN1; SMN2 (0.37) | CYP2C19ALDH1A1 | |
| SCHEMBL21393794 | 0.61 | KDM4E (0.34) | CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL696352 | 0.60 | THRB (0.56) | CYP1A2ALDH1A1 | |
| SCHEMBL6578250 | 0.60 | KDM4E (0.43) | CYP1A2ALDH1A1 | |
| SCHEMBL12824158 | 0.59 | THRB (0.48) | CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019182925-A1 | OXADIAZOLE TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2019-09-26 | — | — | WO | disclosed |