Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | VHL | P40337 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5909175 | 0.83 | MEN1 (0.52) | MEN1KMT2AFAAHMAPK1TSHR | |
| SCHEMBL3313335 | 0.80 | MEN1 (0.50) | MEN1KMT2AFAAHMAPK1TSHR | |
| SCHEMBL40805 | 0.80 | MEN1 (0.50) | MEN1KMT2AFAAHMAPK1TSHR | |
| SCHEMBL17531327 | 0.80 | MEN1 (0.42) | MEN1KMT2AFAAHMAPK1TSHR | |
| SCHEMBL8229956 | 0.80 | MEN1 (0.52) | MEN1KMT2AFAAHMAPK1TSHR | |
| SCHEMBL13368149 | 0.78 | MEN1 (0.61) | MEN1KMT2AFAAHMAPK1TSHR | |
| SCHEMBL21617351 | 0.77 | RXFP1 (0.44) | MEN1KMT2AFAAHMAPK1TSHR | |
| SCHEMBL14458150 | 0.77 | MAPK1 (0.44) | MEN1KMT2AFAAHMAPK1TSHR | |
| SCHEMBL2363846 | 0.77 | CYP3A4 (0.43) | MEN1KMT2ACA1CA2ALDH1A1 | |
| SCHEMBL3467870 | 0.77 | FAAH (0.70) | MEN1KMT2AFAAHMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100577663-C | Fused heterocyclic kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2010-01-06 | — | — | CN | claimed |
| CN-1051733-A | Acyl-CoA: cholesteryl transferase inhibitor | WARNER LAMBERT CO (US) | 1991-05-29 | — | — | CN | claimed |
| EP-4144782-A1 | POLYMERIC SOLUBLE SUPPORT, PROCESS FOR THE SYNTHESIS THEREOF AND USES THEREOF | Synhelix (FR) | 2023-03-08 | — | — | EP | disclosed |
| US-11078168-B2 | Substituted N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase | Phenex Discovery Verwaltungs-GmbH (DE) | 2021-08-03 | — | — | US | disclosed |
| US-20190292160-A1 | SUBSTITUTED N-HYDROXYAMIDINOHETEROCYCLES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | Phenex Discovery Verwaltungs-GmbH (DE) | 2019-09-26 | — | — | US | disclosed |
| CN-103460086-B | Color composition for color filter and colour filter | TOYO INK SC HOLDINGS CO.,LTD. (JP) | 2016-05-18 | — | — | CN | disclosed |
| CN-103460086-A | Colored composition for color filters, and color filters | TOYO INK SC HOLDINGS CO LTD | 2013-12-18 | — | — | CN | disclosed |
| CN-101111470-A | Crystalline acat (acyl-coa:cholesterol o-acyltransferase) inhibitor | WARNER LAMBERT CO (US) | 2008-01-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078168-B2 | Substituted N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase | IDO1, IDO2, INMT | MEN1 893/4885KMT2A 654/4885FAAH 281/4885 |
| US-20190292160-A1 | SUBSTITUTED N-HYDROXYAMIDINOHETEROCYCLES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | IDO1, IDO2, INMT | MEN1 893/4885KMT2A 654/4885FAAH 281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.