Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GLS | O94925 | 3/20 | 0.41 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.34 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.34 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29356668 | 1.00 | RAB9A (0.44) | RAB9AGLSFSCN1SMN1; SMN2EGFR | |
| SCHEMBL29357147 | 0.92 | RAB9A (0.47) | RAB9AGLSFSCN1LMNAMAPT | |
| SCHEMBL21394495 | 0.92 | RAB9A (0.47) | RAB9AGLSFSCN1LMNAMAPT | |
| SCHEMBL22479674 | 0.87 | RAB9A (0.44) | RAB9AFSCN1SMN1; SMN2EGFRNPC1 | |
| SCHEMBL21394439 | 0.87 | RAB9A (0.45) | RAB9AGLSSMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL29353835 | 0.87 | RAB9A (0.45) | RAB9AGLSFSCN1LMNAMAPT | |
| SCHEMBL29357953 | 0.87 | RAB9A (0.45) | RAB9AGLSSMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL21394583 | 0.87 | RAB9A (0.45) | RAB9AGLSFSCN1LMNAMAPT | |
| SCHEMBL21394591 | 0.85 | RAB9A (0.45) | RAB9AGLSFSCN1SMN1; SMN2NPC1 | |
| SCHEMBL29356718 | 0.85 | RAB9A (0.45) | RAB9AGLSFSCN1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084800-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084801-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-112312913-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2021-02-02 | — | — | CN | disclosed |
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |