Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GPER1 | Q99527 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22479450 | 0.94 | SCD (0.49) | SCDKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL21394430 | 0.90 | SCD (0.51) | SCDKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL21394882 | 0.88 | SCD (0.52) | SCDKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL29353798 | 0.88 | SCD (0.52) | SCDKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL29353730 | 0.82 | SCD (0.53) | SCDKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL21394972 | 0.82 | SCD (0.53) | SCDKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL21394797 | 0.79 | SCD (0.49) | SCDKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL21394864 | 0.78 | LMNA (0.62) | SCDKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL21395165 | 0.77 | ABL1 (0.61) | SCDKMT2AMEN1MAPTABL1 | |
| SCHEMBL21395007 | 0.77 | RAB9A (0.59) | KMT2ARAB9AMEN1NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |