Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | OGA | O60502 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.38 |
| ▸ | RELA | Q04206 | 3/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394669 | 0.84 | RAB9A (0.56) | MAPTRAB9AGAAKDM4ELMNA | |
| SCHEMBL21394504 | 0.83 | PDE5A (0.46) | MAPTRAB9AGAAKDM4EHTT | |
| SCHEMBL21394850 | 0.81 | ABL1 (0.57) | MAPTRAB9AGAAKDM4ELMNA | |
| SCHEMBL21394796 | 0.81 | POLB (0.59) | MAPTRAB9AGAAKDM4ELMNA | |
| SCHEMBL21394906 | 0.79 | POLB (0.46) | MAPTRAB9AGAAKDM4ELMNA | |
| SCHEMBL21395177 | 0.79 | MEN1 (0.56) | MAPTRAB9AGAAKDM4EHTT | |
| SCHEMBL21395007 | 0.79 | RAB9A (0.59) | MAPTRAB9AGAAKDM4EHTT | |
| SCHEMBL22479443 | 0.79 | MEN1 (0.46) | MAPTRAB9AGAAKDM4ELMNA | |
| SCHEMBL21394882 | 0.78 | SCD (0.52) | MAPTRAB9AGAAKDM4EHTT | |
| SCHEMBL21394864 | 0.78 | LMNA (0.62) | MAPTRAB9AGAAKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |