Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 6/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29358615 | 1.00 | CCR2 (0.50) | CCR2PTGER1CYP2C9KDM4ENR3C2 | |
| SCHEMBL29442824 | 1.00 | CCR2 (0.50) | CCR2PTGER1CYP2C9KDM4ENR3C2 | |
| SCHEMBL3900938 | 0.84 | CCR2 (0.47) | CCR2PTGER1CYP2C9KDM4ECTSL | |
| SCHEMBL21394815 | 0.82 | PTGER1 (0.49) | CCR2PTGER1CYP2C9KDM4ECTSL | |
| SCHEMBL29353829 | 0.82 | PTGER1 (0.49) | CCR2PTGER1CYP2C9KDM4ECTSL | |
| SCHEMBL437390 | 0.82 | ATR (0.52) | CCR2PTGER1CYP2C9ATRP2RX3 | |
| SCHEMBL29840658 | 0.82 | ATR (0.52) | CCR2PTGER1CYP2C9ATRP2RX3 | |
| SCHEMBL21384138 | 0.81 | NR3C2 (0.53) | NR3C2LMNA | |
| SCHEMBL12953977 | 0.81 | IGF1R (0.47) | CCR2PTGER1CYP2C9NR3C2CYP17A1 | |
| SCHEMBL21394859 | 0.81 | KDM4E (0.46) | PTGER1CYP2C9KDM4ECTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084800-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084801-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-112312913-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2021-02-02 | — | — | CN | disclosed |
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |