Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29353829 | 1.00 | PTGER1 (0.49) | PTGER1CYP2C9CDK9MAPTLMNA | |
| SCHEMBL21384164 | 0.85 | MAPT (0.48) | CYP2C9MAPTLMNAKDM4EMAPK1 | |
| SCHEMBL21394568 | 0.82 | CCR2 (0.50) | PTGER1CYP2C9LMNACTSLKDM4E | |
| SCHEMBL29442824 | 0.82 | CCR2 (0.50) | PTGER1CYP2C9LMNACTSLKDM4E | |
| SCHEMBL29358615 | 0.82 | CCR2 (0.50) | PTGER1CYP2C9LMNACTSLKDM4E | |
| SCHEMBL21394859 | 0.77 | KDM4E (0.46) | PTGER1CYP2C9CTSLKDM4E | |
| SCHEMBL29353767 | 0.77 | KDM4E (0.46) | PTGER1CYP2C9CTSLKDM4E | |
| SCHEMBL7257381 | 0.77 | GSK3B (0.43) | PTGER1CYP2C9CDK9MAPK1LCK | |
| Hydrochloric Acid SCHEMBL7410594 | 0.76 | GSK3B (0.42) | PTGER1CYP2C9CDK9MAPK1LCK | |
| SCHEMBL12225872 | 0.73 | GSK3B (0.48) | PTGER1MAPK1LCKDYRK1AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |