Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 5/20 | 0.37 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394586 | 0.91 | RAB9A (0.47) | RAB9ASMN1; SMN2F10PARP1ALDH1A1 | |
| SCHEMBL21394472 | 0.90 | RAB9A (0.47) | RAB9ASMN1; SMN2F10PARP1ALDH1A1 | |
| SCHEMBL29358624 | 0.90 | RAB9A (0.47) | RAB9ASMN1; SMN2F10PARP1ALDH1A1 | |
| SCHEMBL21394661 | 0.89 | CYP11B1 (0.52) | RAB9ACYP11B1CYP11B2PARP1MAPT | |
| SCHEMBL21394664 | 0.89 | RAB9A (0.44) | RAB9ACYP11B1CYP11B2PARP1ALDH1A1 | |
| SCHEMBL21394773 | 0.89 | RAB9A (0.44) | RAB9ASMN1; SMN2F10PARP1ALDH1A1 | |
| SCHEMBL29354631 | 0.89 | RAB9A (0.44) | RAB9ASMN1; SMN2F10PARP1ALDH1A1 | |
| SCHEMBL21394660 | 0.87 | RAB9A (0.47) | RAB9ASMN1; SMN2F10PARP1ALDH1A1 | |
| SCHEMBL29357828 | 0.87 | RAB9A (0.47) | RAB9ASMN1; SMN2F10PARP1ALDH1A1 | |
| SCHEMBL21394829 | 0.87 | RAB9A (0.43) | RAB9ASMN1; SMN2F10GPR52ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |