Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.45 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 3/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394844 | 0.87 | SNCA (0.47) | MEN1KMT2ANR3C2SORT1GPR52 | |
| SCHEMBL29442866 | 0.87 | SNCA (0.47) | MEN1KMT2ANR3C2SORT1GPR52 | |
| SCHEMBL29442876 | 0.82 | NR3C2 (0.44) | MEN1KMT2ANR3C2SORT1GPR52 | |
| SCHEMBL21394865 | 0.80 | NR3C2 (0.47) | NR3C2GPR52GRM5SNCANPC1 | |
| SCHEMBL29358065 | 0.80 | NR3C2 (0.47) | NR3C2GPR52GRM5SNCANPC1 | |
| SCHEMBL21394763 | 0.76 | NPC1 (0.51) | MEN1KMT2ANPC1TP53PKM | |
| SCHEMBL29355382 | 0.76 | NPC1 (0.51) | MEN1KMT2ANPC1TP53PKM | |
| SCHEMBL21394696 | 0.75 | RAB9A (0.52) | MEN1KMT2ANR3C2LMNAKDM5A | |
| SCHEMBL21394488 | 0.73 | MEN1 (0.48) | MEN1KMT2ASNCANPC1TP53 | |
| SCHEMBL14009842 | 0.72 | CDC7 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |