Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 5/20 | 0.47 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29442866 | 1.00 | SNCA (0.47) | SNCAGRM5SORT1NR3C2GPR52 | |
| SCHEMBL21394865 | 0.88 | NR3C2 (0.47) | SNCAGRM5NR3C2GPR52ANO1 | |
| SCHEMBL29358065 | 0.88 | NR3C2 (0.47) | SNCAGRM5NR3C2GPR52ANO1 | |
| SCHEMBL21394614 | 0.87 | MEN1 (0.48) | SNCAGRM5SORT1NR3C2GPR52 | |
| SCHEMBL21394734 | 0.82 | NR3C2 (0.49) | SNCANR3C2GPR52RETANO1 | |
| SCHEMBL29442811 | 0.82 | SNCA (0.48) | SNCAGRM5NR3C2GPR52RET | |
| SCHEMBL21394469 | 0.82 | SNCA (0.48) | SNCAGRM5NR3C2GPR52RET | |
| SCHEMBL29442876 | 0.80 | NR3C2 (0.44) | GRM5SORT1NR3C2GPR52ANO1 | |
| SCHEMBL21395171 | 0.80 | NPC1 (0.47) | SNCAGRM5NR3C2RETNPC1 | |
| SCHEMBL21394764 | 0.80 | NPC1 (0.50) | SNCAGRM5RETNPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-112312913-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2021-02-02 | — | — | CN | disclosed |
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |