Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 9/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394779 | 0.89 | GPR6 (0.41) | GRM5 | |
| SCHEMBL29356981 | 0.89 | GPR6 (0.41) | GRM5 | |
| SCHEMBL21395179 | 0.84 | GCK (0.42) | CYP3A4 | |
| SCHEMBL21394938 | 0.84 | TMPRSS4 (0.47) | KCNH2 | |
| SCHEMBL21395002 | 0.83 | TMPRSS4 (0.41) | CYP3A4 | |
| SCHEMBL21394745 | 0.82 | TMPRSS4 (0.39) | CYP3A4 | |
| SCHEMBL21395016 | 0.82 | CHEK1 (0.40) | CYP3A4 | |
| SCHEMBL21394875 | 0.81 | EP300 (0.42) | — | |
| SCHEMBL29358580 | 0.81 | EP300 (0.42) | — | |
| SCHEMBL21394731 | 0.80 | CYP3A4 (0.42) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |