Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.53 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | VNN1 | O95497 | 3/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 3/20 | 0.44 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394753 | 0.85 | SIRT2 (0.56) | SIRT2TMPRSS4MEN1KMT2AVNN1 | |
| SCHEMBL29358142 | 0.85 | SIRT2 (0.56) | SIRT2TMPRSS4MEN1KMT2AVNN1 | |
| SCHEMBL21395069 | 0.82 | SCD (0.47) | SIRT2MEN1KMT2AVNN1P4HTM | |
| SCHEMBL21395259 | 0.78 | MEN1 (0.49) | MEN1KMT2ASCDNPC1 | |
| SCHEMBL29354534 | 0.78 | MEN1 (0.49) | MEN1KMT2ASCDNPC1 | |
| SCHEMBL15819591 | 0.78 | SIRT2 (0.55) | SIRT2MEN1KMT2AVNN1NPC1 | |
| SCHEMBL29357102 | 0.76 | TMPRSS4 (0.52) | SIRT2TMPRSS4MEN1KMT2ABACE1 | |
| SCHEMBL29442822 | 0.76 | SIRT2 (0.50) | SIRT2TMPRSS4MEN1KMT2ANPC1 | |
| SCHEMBL21384381 | 0.76 | SIRT2 (0.50) | SIRT2TMPRSS4MEN1KMT2ANPC1 | |
| SCHEMBL21395196 | 0.76 | TMPRSS4 (0.52) | SIRT2TMPRSS4MEN1KMT2ABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |