Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | VNN1 | O95497 | 2/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29357578 | 0.85 | SIRT2 (0.47) | P4HTMSIRT2ALDH1A1F10MEN1 | |
| SCHEMBL21394834 | 0.85 | SIRT2 (0.47) | P4HTMSIRT2ALDH1A1F10MEN1 | |
| SCHEMBL21395188 | 0.83 | MEN1 (0.57) | SIRT2ALDH1A1F10MEN1KMT2A | |
| SCHEMBL21394719 | 0.82 | SIRT2 (0.53) | SCDP4HTMSIRT2MEN1KMT2A | |
| SCHEMBL29353894 | 0.78 | SCD (0.48) | SCDALDH1A1F10MEN1KMT2A | |
| SCHEMBL21394876 | 0.78 | SCD (0.48) | SCDALDH1A1F10MEN1KMT2A | |
| SCHEMBL3646298 | 0.75 | P4HTM (0.62) | P4HTMALDH1A1MEN1KMT2AVNN1 | |
| SCHEMBL21394997 | 0.75 | KCNQ3 (0.57) | SCDSIRT2ALDH1A1F10KCNQ3 | |
| SCHEMBL21394396 | 0.74 | KCNQ3 (0.47) | ALDH1A1KCNQ3KCNQ2 | |
| SCHEMBL21395259 | 0.73 | MEN1 (0.49) | SCDALDH1A1F10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |