Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.56 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.42 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394753 | 1.00 | SIRT2 (0.56) | SIRT2TMPRSS4MEN1KMT2AALDH1A1 | |
| SCHEMBL29442822 | 0.88 | SIRT2 (0.50) | SIRT2TMPRSS4MEN1KMT2AALDH1A1 | |
| SCHEMBL21384381 | 0.88 | SIRT2 (0.50) | SIRT2TMPRSS4MEN1KMT2AALDH1A1 | |
| SCHEMBL21395196 | 0.86 | TMPRSS4 (0.52) | SIRT2TMPRSS4MEN1KMT2ABACE1 | |
| SCHEMBL29357102 | 0.86 | TMPRSS4 (0.52) | SIRT2TMPRSS4MEN1KMT2ABACE1 | |
| SCHEMBL21394767 | 0.85 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1HIF1ASNCA | |
| SCHEMBL29358525 | 0.85 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1HIF1ASNCA | |
| SCHEMBL21394719 | 0.85 | SIRT2 (0.53) | SIRT2TMPRSS4MEN1KMT2AEGLN2 | |
| SCHEMBL21394959 | 0.84 | TMPRSS4 (0.49) | SIRT2TMPRSS4MEN1KMT2ABACE1 | |
| SCHEMBL21395185 | 0.83 | TMPRSS4 (0.49) | SIRT2TMPRSS4MEN1KMT2ABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084800-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084801-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| EP-3941908-A1 | COMPOUNDS AND USES THEREOF | Yumanity Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |