Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 4/20 | 0.48 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.48 |
| ▸ | WNT1 | P04628 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394997 | 0.86 | KCNQ3 (0.57) | KCNQ3KCNQ2MAOBSIRT2NPC1 | |
| SCHEMBL21395118 | 0.84 | KCNQ3 (0.43) | KCNQ3KCNQ2MAOBSIRT2NPC1 | |
| SCHEMBL21395019 | 0.83 | PARP1 (0.53) | KCNQ3KCNQ2MAOBNPC1RAB9A | |
| SCHEMBL21395146 | 0.82 | KCNQ3 (0.44) | KCNQ3KCNQ2SIRT2NPC1RAB9A | |
| SCHEMBL21395078 | 0.82 | CHEK1 (0.48) | KCNQ3KCNQ2SIRT2NPC1RAB9A | |
| SCHEMBL21394650 | 0.81 | PARP1 (0.41) | KCNQ3KCNQ2MAOBNPC1RAB9A | |
| SCHEMBL21395010 | 0.80 | TMPRSS4 (0.44) | KCNQ3KCNQ2SIRT2NPC1RAB9A | |
| SCHEMBL21394718 | 0.75 | NPC1 (0.42) | KCNQ3KCNQ2GSK3BMAOBSIRT2 | |
| SCHEMBL21394396 | 0.74 | KCNQ3 (0.47) | KCNQ3KCNQ2ALDH1A1 | |
| SCHEMBL21394712 | 0.74 | PPARG (0.41) | KCNQ3KCNQ2MAOBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |