Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | WNT3A | P56704 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 4/20 | 0.41 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21395019 | 0.88 | PARP1 (0.53) | PARP1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL21394654 | 0.87 | WNT3A (0.44) | PARP1WNT3ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL21394854 | 0.86 | WNT3A (0.52) | WNT3ASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL29359193 | 0.86 | WNT3A (0.52) | WNT3ASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL21394732 | 0.81 | KCNQ3 (0.48) | PARP1SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL21395182 | 0.81 | GSK3B (0.44) | SMN1; SMN2NPC1RAB9AALDH1A1PKM | |
| SCHEMBL21394645 | 0.80 | DEGS1 (0.42) | ALDH1A1KCNQ3KCNQ2MAOBF10 | |
| SCHEMBL21394997 | 0.80 | KCNQ3 (0.57) | SMN1; SMN2NPC1RAB9AALDH1A1PKM | |
| SCHEMBL21395118 | 0.80 | KCNQ3 (0.43) | SMN1; SMN2NPC1RAB9AALDH1A1PKM | |
| SCHEMBL21394718 | 0.80 | NPC1 (0.42) | PARP1SMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |