Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GRM5 | P41594 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29353935 | 1.00 | RAB9A (0.46) | RAB9AGRM5KDM4EAHRPARP1 | |
| SCHEMBL21395043 | 0.92 | RAB9A (0.47) | RAB9AGRM5KDM4EAHRPARP1 | |
| SCHEMBL29355445 | 0.92 | RAB9A (0.47) | RAB9AGRM5KDM4EAHRPARP1 | |
| SCHEMBL29359190 | 0.90 | RAB9A (0.47) | RAB9AKDM4EPARP1POLBALDH1A1 | |
| SCHEMBL29358624 | 0.90 | RAB9A (0.47) | RAB9APARP1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL21394472 | 0.90 | RAB9A (0.47) | RAB9APARP1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL21394808 | 0.90 | RAB9A (0.47) | RAB9AKDM4EPARP1POLBALDH1A1 | |
| SCHEMBL21394664 | 0.89 | RAB9A (0.44) | RAB9AGRM5AHRPARP1ALDH1A1 | |
| SCHEMBL21394559 | 0.89 | RAB9A (0.44) | RAB9AKDM4EAHRPARP1POLB | |
| SCHEMBL29358581 | 0.89 | RAB9A (0.44) | RAB9AKDM4EAHRPARP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084800-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084801-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-112312913-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2021-02-02 | — | — | CN | disclosed |
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |