Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21395043 | 1.00 | RAB9A (0.47) | RAB9ANPY5RAHRPARP1GPR52 | |
| SCHEMBL29353757 | 0.93 | RAB9A (0.43) | RAB9AGPR52GRM5ALDH1A1 | |
| SCHEMBL21394829 | 0.93 | RAB9A (0.43) | RAB9AGPR52GRM5ALDH1A1 | |
| SCHEMBL21394770 | 0.92 | RAB9A (0.46) | RAB9AAHRPARP1GRM5ALDH1A1 | |
| SCHEMBL29353935 | 0.92 | RAB9A (0.46) | RAB9AAHRPARP1GRM5ALDH1A1 | |
| SCHEMBL21394664 | 0.91 | RAB9A (0.44) | RAB9AAHRPARP1GRM5CSF1R | |
| SCHEMBL29358581 | 0.91 | RAB9A (0.44) | RAB9AAHRPARP1ALDH1A1MAPT | |
| SCHEMBL21394559 | 0.91 | RAB9A (0.44) | RAB9AAHRPARP1ALDH1A1MAPT | |
| SCHEMBL21384478 | 0.91 | RAB9A (0.46) | RAB9AAHRPARP1GPR52CSF1R | |
| SCHEMBL29356974 | 0.91 | RAB9A (0.46) | RAB9AAHRPARP1GPR52CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084800-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084801-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| EP-3941908-A1 | COMPOUNDS AND USES THEREOF | Yumanity Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |