Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | FPR1 | P21462 | 2/20 | 0.37 |
| ▸ | FPR2 | P25090 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29355492 | 1.00 | RAB9A (0.42) | RAB9AMAPTALDH1A1LMNAMAPK1 | |
| Trifluoroacetic Acid SCHEMBL28525655 | 0.94 | RAB9A (0.38) | RAB9AMAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL29354631 | 0.86 | RAB9A (0.44) | RAB9AMAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL21394773 | 0.86 | RAB9A (0.44) | RAB9AMAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL21394447 | 0.85 | RAB9A (0.44) | RAB9AMAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL21394570 | 0.85 | RAB9A (0.45) | RAB9AMAPTLMNARXFP1NPC1 | |
| SCHEMBL21394444 | 0.82 | RAB9A (0.46) | RAB9AMAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL29356245 | 0.82 | RAB9A (0.46) | RAB9AMAPTALDH1A1LMNAMAPK1 | |
| SCHEMBL21394665 | 0.81 | RAB9A (0.50) | RAB9AMAPTALDH1A1LMNANPC1 | |
| SCHEMBL21394583 | 0.81 | RAB9A (0.45) | RAB9AMAPTLMNARXFP1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |