Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 7/20 | 0.46 |
| ▸ | MAOA | P21397 | 4/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29357318 | 1.00 | MEN1 (0.48) | MEN1KMT2AL3MBTL1MAOBMAOA | |
| SCHEMBL22479581 | 0.89 | MEN1 (0.50) | MEN1KMT2AL3MBTL1MAOBMAOA | |
| SCHEMBL21394760 | 0.85 | L3MBTL1 (0.47) | MEN1KMT2AL3MBTL1TSHRHTT | |
| SCHEMBL29354586 | 0.85 | L3MBTL1 (0.47) | MEN1KMT2AL3MBTL1TSHRHTT | |
| SCHEMBL29357070 | 0.85 | L3MBTL1 (0.47) | MEN1KMT2AL3MBTL1TSHRHTT | |
| SCHEMBL21394806 | 0.85 | L3MBTL1 (0.47) | MEN1KMT2AL3MBTL1TSHRHTT | |
| SCHEMBL21394741 | 0.85 | L3MBTL1 (0.55) | MEN1KMT2AL3MBTL1MAOBMAOA | |
| SCHEMBL21395089 | 0.84 | MEN1 (0.52) | MEN1KMT2AMAOBMAOARXRA | |
| SCHEMBL21394399 | 0.81 | KMT2A (0.47) | MEN1KMT2AL3MBTL1TSHRHTT | |
| SCHEMBL21395033 | 0.81 | L3MBTL1 (0.45) | MEN1KMT2AL3MBTL1MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084800-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084801-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-112312913-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2021-02-02 | — | — | CN | disclosed |
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |