Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 5/20 | 0.50 |
| ▸ | MAOA | P21397 | 3/20 | 0.50 |
| ▸ | GCK | P35557 | 3/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394948 | 0.89 | MEN1 (0.54) | MEN1KMT2AMAOBMAOAGCK | |
| SCHEMBL29358548 | 0.89 | MEN1 (0.54) | MEN1KMT2AMAOBMAOAGCK | |
| SCHEMBL21394825 | 0.85 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL29354520 | 0.85 | MEN1 (0.53) | MEN1KMT2AGCKALDH1A1NPC1 | |
| SCHEMBL29356860 | 0.85 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL21394759 | 0.85 | MEN1 (0.53) | MEN1KMT2AGCKALDH1A1NPC1 | |
| SCHEMBL21394841 | 0.84 | MEN1 (0.48) | MEN1KMT2AMAOBMAOARXRA | |
| SCHEMBL29357318 | 0.84 | MEN1 (0.48) | MEN1KMT2AMAOBMAOARXRA | |
| SCHEMBL22479582 | 0.81 | MEN1 (0.46) | MEN1KMT2AMAOBMAOAGCK | |
| SCHEMBL21395181 | 0.80 | GCK (0.54) | MEN1KMT2AGCKALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |