Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1778675 | 0.79 | MEN1 (0.46) | ALDH1A1L3MBTL1MAPTLMNAMEN1 | |
| SCHEMBL1778116 | 0.79 | MEN1 (0.46) | ALDH1A1L3MBTL1MAPTLMNAMEN1 | |
| SCHEMBL21394860 | 0.78 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1MAPTLMNATSHR | |
| SCHEMBL2898384 | 0.78 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1MAPTLMNATSHR | |
| SCHEMBL286957 | 0.73 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1MAPTLMNATSHR | |
| SCHEMBL22479596 | 0.72 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1MAPTLMNATSHR | |
| SCHEMBL18157898 | 0.71 | MEN1 (0.56) | ALDH1A1L3MBTL1MAPTLMNATSHR | |
| SCHEMBL2890719 | 0.71 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1MAPTLMNATSHR | |
| SCHEMBL31728945 | 0.70 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1MAPTLMNATSHR | |
| SCHEMBL13210632 | 0.70 | ALDH1A1 (0.55) | ALDH1A1LMNAMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |