Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2898384 | 0.83 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL2890719 | 0.82 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL2306577 | 0.77 | MAPT (0.55) | ALDH1A1L3MBTL1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL21394860 | 0.77 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL286957 | 0.74 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL31728945 | 0.74 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL7858483 | 0.74 | TSHR (0.66) | ALDH1A1L3MBTL1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL31728764 | 0.72 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL21394858 | 0.72 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL21395235 | 0.69 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1MAPTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |