Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.40 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3393182 | 0.81 | GLA (0.48) | GLAFOLH1SLC6A2SLC6A4CNR1 | |
| SCHEMBL3392965 | 0.81 | GLA (0.48) | GLAFOLH1SLC6A2SLC6A4CNR1 | |
| SCHEMBL4006758 | 0.80 | LOXL2 (0.44) | DPP4CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL29869064 | 0.76 | PNMT (0.55) | SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL11568409 | 0.76 | PNMT (0.55) | SLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL30646949 | 0.75 | GLA (0.51) | GLAFOLH1MRGPRX4MEP1AMEP1B | |
| SCHEMBL253203 | 0.75 | GLA (0.51) | GLAFOLH1MRGPRX4MEP1AMEP1B | |
| SCHEMBL21395003 | 0.75 | SLC1A1 (0.46) | ALDH1A1 | |
| SCHEMBL27659905 | 0.74 | GLA (0.50) | GLAFOLH1SLC6A2SLC6A4MRGPRX4 | |
| SCHEMBL2660512 | 0.74 | GLA (0.58) | GLAFOLH1SLC6A2SLC6A4MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |