Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.43 |
| ▸ | CDK2 | P24941 | 5/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 4/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29356596 | 1.00 | SCD (0.45) | SCDCCNE1CDK2CDK5PSEN1 | |
| SCHEMBL21395247 | 0.89 | PSEN1 (0.48) | CCNE1CDK2CDK5PSEN1PSEN2 | |
| SCHEMBL21394890 | 0.87 | S1PR3 (0.46) | SCDCCNE1CDK2CDK5LCK | |
| SCHEMBL29358752 | 0.87 | S1PR3 (0.46) | SCDCCNE1CDK2CDK5LCK | |
| SCHEMBL21395005 | 0.86 | CCNE1 (0.47) | SCDCCNE1CDK2CDK5LCK | |
| SCHEMBL29357987 | 0.86 | CCNE1 (0.47) | SCDCCNE1CDK2CDK5LCK | |
| SCHEMBL21394896 | 0.86 | P2RY2 (0.42) | SCDCCNE1CDK2CDK5PSEN1 | |
| SCHEMBL21395300 | 0.85 | PSEN1 (0.45) | CCNE1CDK2CDK5PSEN1PSEN2 | |
| SCHEMBL21395055 | 0.84 | PSEN1 (0.42) | SCDCCNE1CDK2CDK5PSEN1 | |
| SCHEMBL5025975 | 0.83 | KDM4E (0.42) | CCNE1CDK2CDK5PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |