Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | SCD | O00767 | 2/20 | 0.46 |
| ▸ | LCK | P06239 | 2/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29357987 | 1.00 | CCNE1 (0.47) | CCNE1CDK2CDK5SCDLCK | |
| SCHEMBL34467367 | 0.88 | CDK2 (0.47) | CCNE1CDK2CDK5SCDLCK | |
| SCHEMBL21394890 | 0.86 | S1PR3 (0.46) | CCNE1CDK2CDK5SCDLCK | |
| SCHEMBL21394898 | 0.86 | SCD (0.45) | CCNE1CDK2CDK5SCDLCK | |
| SCHEMBL29356596 | 0.86 | SCD (0.45) | CCNE1CDK2CDK5SCDLCK | |
| SCHEMBL29358752 | 0.86 | S1PR3 (0.46) | CCNE1CDK2CDK5SCDLCK | |
| SCHEMBL21384077 | 0.85 | CCNE1 (0.49) | CCNE1CDK2CDK5SCDGLS | |
| SCHEMBL29355446 | 0.82 | TSHR (0.54) | CCNE1CDK2CDK5SCDGLS | |
| SCHEMBL21394896 | 0.81 | P2RY2 (0.42) | CCNE1CDK2CDK5SCDLCK | |
| SCHEMBL21394886 | 0.79 | P2RY2 (0.53) | CCNE1CDK2CDK5P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |