Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 2/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.45 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.41 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29358752 | 1.00 | S1PR3 (0.46) | S1PR3SCDP2RY2CCNE1CDK2 | |
| SCHEMBL21394898 | 0.87 | SCD (0.45) | S1PR3SCDP2RY2CCNE1CDK2 | |
| SCHEMBL29356596 | 0.87 | SCD (0.45) | S1PR3SCDP2RY2CCNE1CDK2 | |
| SCHEMBL21395232 | 0.87 | P2RY2 (0.43) | S1PR3SCDP2RY2CCNE1CDK2 | |
| SCHEMBL21394886 | 0.86 | P2RY2 (0.53) | P2RY2CCNE1CDK2CDK5FFAR2 | |
| SCHEMBL29357987 | 0.86 | CCNE1 (0.47) | SCDP2RY2CCNE1CDK2CDK5 | |
| SCHEMBL21395005 | 0.86 | CCNE1 (0.47) | SCDP2RY2CCNE1CDK2CDK5 | |
| SCHEMBL21395055 | 0.84 | PSEN1 (0.42) | S1PR3SCDP2RY2CCNE1CDK2 | |
| SCHEMBL21394896 | 0.83 | P2RY2 (0.42) | S1PR3SCDP2RY2CCNE1CDK2 | |
| SCHEMBL5026040 | 0.83 | MAPT (0.43) | S1PR3P2RY2CCNE1CDK2CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |