Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 6/20 | 0.47 |
| ▸ | CDK2 | P24941 | 6/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.47 |
| ▸ | LCK | P06239 | 4/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CCNH | P51946 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29356948 | 1.00 | CCNE1 (0.47) | CCNE1CDK2CDK5LCKP2RY2 | |
| SCHEMBL1924303 | 0.83 | CCNE1 (0.41) | CCNE1CDK2CDK5LCKP2RY2 | |
| SCHEMBL1924827 | 0.83 | CCNE1 (0.41) | CCNE1CDK2CDK5LCKP2RY2 | |
| SCHEMBL12361180 | 0.83 | CCNE1 (0.41) | CCNE1CDK2CDK5LCKP2RY2 | |
| SCHEMBL21384102 | 0.82 | CCNE1 (0.48) | CCNE1CDK2CDK5LCKSMN1; SMN2 | |
| SCHEMBL21394886 | 0.81 | P2RY2 (0.53) | CCNE1CDK2CDK5P2RY2 | |
| SCHEMBL21394901 | 0.80 | CCNE1 (0.41) | CCNE1CDK2CDK5LCKP2RY2 | |
| SCHEMBL29358389 | 0.80 | CCNE1 (0.41) | CCNE1CDK2CDK5LCKP2RY2 | |
| SCHEMBL21395245 | 0.80 | CCNE1 (0.41) | CCNE1CDK2CDK5LCKP2RY2 | |
| SCHEMBL21394890 | 0.80 | S1PR3 (0.46) | CCNE1CDK2CDK5LCKP2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |