Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29357533 | 0.88 | RAB9A (0.55) | RAB9ACES2ALDH1A1FSCN1MAPT | |
| SCHEMBL21394922 | 0.88 | RAB9A (0.55) | RAB9ACES2ALDH1A1FSCN1MAPT | |
| SCHEMBL22479676 | 0.85 | RAB9A (0.43) | RAB9ACES2ALDH1A1FSCN1MAPT | |
| SCHEMBL21394591 | 0.83 | RAB9A (0.45) | RAB9ACES2ALDH1A1FSCN1MAPT | |
| SCHEMBL29356718 | 0.83 | RAB9A (0.45) | RAB9ACES2ALDH1A1FSCN1MAPT | |
| SCHEMBL21394491 | 0.83 | RAB9A (0.43) | RAB9AALDH1A1FSCN1MAPTKDM4E | |
| SCHEMBL29358581 | 0.83 | RAB9A (0.44) | RAB9AALDH1A1FSCN1MAPTNPC1 | |
| SCHEMBL21394559 | 0.83 | RAB9A (0.44) | RAB9AALDH1A1FSCN1MAPTNPC1 | |
| SCHEMBL22479448 | 0.82 | SRC (0.40) | RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL21394934 | 0.81 | KDM4E (0.47) | RAB9AALDH1A1HTTMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |