Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21395137 | 0.89 | LMNA (0.47) | KDM4EHTTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL21394962 | 0.83 | NPC1 (0.48) | KDM4EHTTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL29356723 | 0.83 | ALDH1A1 (0.47) | KDM4EHTTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL21394836 | 0.83 | ALDH1A1 (0.47) | KDM4EHTTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL21395006 | 0.82 | MEN1 (0.52) | SMN1; SMN2ALDH1A1RAB9AKMT2AMEN1 | |
| SCHEMBL29356718 | 0.82 | RAB9A (0.45) | SMN1; SMN2ALDH1A1RAB9AKMT2AMEN1 | |
| SCHEMBL21394591 | 0.82 | RAB9A (0.45) | SMN1; SMN2ALDH1A1RAB9AKMT2AMEN1 | |
| SCHEMBL21394887 | 0.82 | MAPT (0.47) | KDM4EHTTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL21394882 | 0.81 | SCD (0.52) | KDM4EHTTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL29353798 | 0.81 | SCD (0.52) | KDM4EHTTLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |