Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | BRD2 | P25440 | 1/20 | 0.41 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.41 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394486 | 0.89 | ALDH1A1 (0.53) | TP53BRD4MAPTLMNABRD2 | |
| SCHEMBL29356259 | 0.89 | ALDH1A1 (0.53) | TP53BRD4MAPTLMNABRD2 | |
| SCHEMBL21394445 | 0.88 | CREBBP (0.45) | TP53BRD4SMN1; SMN2P2RY14NPC1 | |
| SCHEMBL29357564 | 0.88 | CREBBP (0.45) | TP53BRD4SMN1; SMN2P2RY14NPC1 | |
| SCHEMBL21395138 | 0.88 | MAPT (0.47) | TP53BRD4MAPTLMNABRD2 | |
| SCHEMBL29358552 | 0.85 | TP53 (0.46) | TP53BRD4MAPTLMNABRD2 | |
| SCHEMBL21384386 | 0.85 | TP53 (0.46) | TP53BRD4MAPTLMNABRD2 | |
| SCHEMBL29356949 | 0.81 | ABCC8 (0.46) | BRD4LMNASMN1; SMN2ALDH1A1P2RY14 | |
| SCHEMBL21384455 | 0.81 | ABCC8 (0.46) | BRD4LMNASMN1; SMN2ALDH1A1P2RY14 | |
| SCHEMBL21394582 | 0.78 | TSHR (0.47) | BRD4MAPTLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |