Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 13/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29357021 | 1.00 | LCK (0.42) | LCKACP1HDAC4HDAC7HDAC5 | |
| SCHEMBL21395280 | 0.89 | LCK (0.50) | LCK | |
| SCHEMBL29353882 | 0.88 | LCK (0.45) | LCKACP1 | |
| SCHEMBL21384103 | 0.88 | LCK (0.45) | LCKACP1 | |
| SCHEMBL21384113 | 0.84 | ACP1 (0.42) | ACP1HDAC4HDAC7HDAC5 | |
| SCHEMBL34467451 | 0.81 | LCK (0.43) | LCK | |
| SCHEMBL21394898 | 0.80 | SCD (0.45) | LCK | |
| SCHEMBL29356596 | 0.80 | SCD (0.45) | LCK | |
| SCHEMBL6837299 | 0.76 | LCK (0.46) | LCK | |
| SCHEMBL27459853 | 0.74 | LCK (0.44) | LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |