Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | GPR6 | P46095 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 6/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.38 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394995 | 0.88 | NTRK1 (0.45) | ALDH1A1MAPTL3MBTL1TSHRKDM4E | |
| SCHEMBL21394742 | 0.85 | MAPT (0.44) | SIRT2ALDH1A1MAPTL3MBTL1GPR6 | |
| SCHEMBL21394628 | 0.85 | ALDH1A1 (0.41) | SIRT2ALDH1A1MAPTL3MBTL1EP300 | |
| SCHEMBL29357585 | 0.85 | ALDH1A1 (0.41) | SIRT2ALDH1A1MAPTL3MBTL1EP300 | |
| SCHEMBL29358376 | 0.84 | SIRT2 (0.42) | SIRT2ALDH1A1MAPTL3MBTL1EP300 | |
| SCHEMBL21394629 | 0.84 | SIRT2 (0.42) | SIRT2ALDH1A1MAPTL3MBTL1EP300 | |
| SCHEMBL21394990 | 0.84 | DEGS1 (0.41) | SIRT2TMPRSS4EP300GPR6NTRK1 | |
| SCHEMBL21395122 | 0.84 | L3MBTL1 (0.43) | SIRT2ALDH1A1MAPTL3MBTL1TMPRSS4 | |
| SCHEMBL21394578 | 0.83 | L3MBTL1 (0.46) | ALDH1A1MAPTL3MBTL1TSHRKDM4E | |
| SCHEMBL29355468 | 0.83 | L3MBTL1 (0.46) | ALDH1A1MAPTL3MBTL1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |