Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 3/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394956 | 0.91 | AHR (0.44) | AHRNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL21395013 | 0.89 | NPC1 (0.44) | AHRNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL21394647 | 0.85 | AHR (0.46) | AHRFSCN1NPC1RAB9AALDH1A1 | |
| SCHEMBL29353805 | 0.85 | AHR (0.45) | AHRFSCN1NPC1RAB9AALDH1A1 | |
| SCHEMBL21394786 | 0.85 | AHR (0.45) | AHRFSCN1NPC1RAB9AALDH1A1 | |
| SCHEMBL29442848 | 0.81 | SNCA (0.45) | FSCN1AKT1SCD | |
| SCHEMBL21394730 | 0.81 | SNCA (0.45) | FSCN1AKT1SCD | |
| SCHEMBL22479679 | 0.80 | NPC1 (0.42) | AHRNPC1RAB9AALDH1A1PKM | |
| SCHEMBL21394641 | 0.79 | TSHR (0.47) | NPC1RAB9AALDH1A1PKMTSHR | |
| SCHEMBL29356991 | 0.79 | TSHR (0.47) | NPC1RAB9AALDH1A1PKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |