Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | SCD | O00767 | 14/20 | 0.42 |
| ▸ | SCD5 | Q86SK9 | 9/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29442848 | 1.00 | SNCA (0.45) | SNCASCDSCD5AKT1GRM4 | |
| SCHEMBL21395093 | 0.89 | LMNA (0.43) | SNCAFSCN1HDAC3HDAC1HDAC2 | |
| SCHEMBL21395014 | 0.81 | AHR (0.44) | SCDAKT1FSCN1 | |
| SCHEMBL21384504 | 0.79 | SNCA (0.48) | SNCASCDSCD5MMP13 | |
| SCHEMBL29353720 | 0.79 | SNCA (0.48) | SNCASCDSCD5MMP13 | |
| SCHEMBL29358085 | 0.76 | NPC1 (0.48) | SNCASCD | |
| SCHEMBL21394658 | 0.76 | NPC1 (0.48) | SNCASCD | |
| SCHEMBL29356991 | 0.76 | TSHR (0.47) | SNCASCD | |
| SCHEMBL21394641 | 0.76 | TSHR (0.47) | SNCASCD | |
| SCHEMBL21384460 | 0.75 | SNCA (0.45) | SNCASCDSCD5FSCN1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| EP-3941908-A1 | COMPOUNDS AND USES THEREOF | Yumanity Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |
| CN-112312913-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2021-02-02 | — | — | CN | disclosed |
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |