Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | F10 | P00742 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | GCK | P35557 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394657 | 0.90 | ALDH1A1 (0.49) | ALDH1A1F10SMN1; SMN2NPC1PKM | |
| SCHEMBL21394651 | 0.90 | ALDH1A1 (0.49) | ALDH1A1F10SMN1; SMN2NPC1PKM | |
| SCHEMBL21394722 | 0.88 | ALDH1A1 (0.45) | ALDH1A1F10SMN1; SMN2NPC1PKM | |
| SCHEMBL29357095 | 0.84 | F10 (0.53) | ALDH1A1F10SMN1; SMN2NPC1PKM | |
| SCHEMBL21394880 | 0.84 | F10 (0.53) | ALDH1A1F10SMN1; SMN2NPC1PKM | |
| SCHEMBL21394466 | 0.83 | ALDH1A1 (0.48) | ALDH1A1F10SMN1; SMN2NPC1PKM | |
| SCHEMBL21395090 | 0.83 | ALDH1A1 (0.51) | ALDH1A1F10SMN1; SMN2TSHRRAB9A | |
| SCHEMBL29356935 | 0.83 | ALDH1A1 (0.48) | ALDH1A1F10SMN1; SMN2NPC1PKM | |
| SCHEMBL22479547 | 0.82 | ALDH1A1 (0.50) | ALDH1A1F10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL21394834 | 0.82 | SIRT2 (0.47) | ALDH1A1F10SMN1; SMN2NPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |