Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22479547 | 0.93 | ALDH1A1 (0.50) | ALDH1A1P4HTMF10MEN1KMT2A | |
| SCHEMBL21394728 | 0.90 | ALDH1A1 (0.49) | ALDH1A1P4HTMF10MEN1KMT2A | |
| SCHEMBL21384159 | 0.88 | ALDH1A1 (0.47) | ALDH1A1P4HTMF10MEN1KMT2A | |
| SCHEMBL21394716 | 0.86 | P4HTM (0.45) | ALDH1A1P4HTMF10MEN1KMT2A | |
| SCHEMBL21395182 | 0.86 | GSK3B (0.44) | ALDH1A1P4HTMF10SMN1; SMN2KLKB1 | |
| SCHEMBL29358525 | 0.85 | ALDH1A1 (0.47) | ALDH1A1P4HTMF10MEN1KMT2A | |
| SCHEMBL21394767 | 0.85 | ALDH1A1 (0.47) | ALDH1A1P4HTMF10MEN1KMT2A | |
| SCHEMBL21394657 | 0.85 | ALDH1A1 (0.49) | ALDH1A1F10MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21394651 | 0.85 | ALDH1A1 (0.49) | ALDH1A1F10MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21394466 | 0.85 | ALDH1A1 (0.48) | ALDH1A1P4HTMF10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |