Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | FLT1 | P17948 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 7/20 | 0.43 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29353894 | 1.00 | SCD (0.48) | SCDCREBBPMEN1KMT2ALMNA | |
| SCHEMBL29356860 | 0.85 | ALDH1A1 (0.48) | CREBBPMEN1KMT2ALMNAMAPT | |
| SCHEMBL21394825 | 0.85 | ALDH1A1 (0.48) | CREBBPMEN1KMT2ALMNAMAPT | |
| SCHEMBL22479687 | 0.84 | CREBBP (0.51) | CREBBPMEN1KMT2ALMNAMAPT | |
| SCHEMBL21395259 | 0.84 | MEN1 (0.49) | SCDMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL29354534 | 0.84 | MEN1 (0.49) | SCDMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL29358548 | 0.83 | MEN1 (0.54) | CREBBPMEN1KMT2AALDH1A1F10 | |
| SCHEMBL21394948 | 0.83 | MEN1 (0.54) | CREBBPMEN1KMT2AALDH1A1F10 | |
| SCHEMBL21394506 | 0.81 | RAB9A (0.49) | KMT2ALMNAMAPTALDH1A1F10 | |
| SCHEMBL21395089 | 0.79 | MEN1 (0.52) | CREBBPMEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084800-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084801-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| EP-3941908-A1 | COMPOUNDS AND USES THEREOF | Yumanity Therapeutics, Inc. (US) | 2022-01-26 | — | — | EP | disclosed |
| CN-112312913-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2021-02-02 | — | — | CN | disclosed |
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |