Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394840 | 0.91 | RAB9A (0.47) | MEN1KMT2ANPC1CASP3RAB9A | |
| SCHEMBL29355464 | 0.91 | RAB9A (0.47) | MEN1KMT2ANPC1CASP3RAB9A | |
| SCHEMBL21395077 | 0.88 | GCK (0.51) | MEN1KMT2ACYP3A4POLBGRM5 | |
| SCHEMBL21394862 | 0.88 | GCK (0.52) | MEN1KMT2ANPC1CASP3RAB9A | |
| SCHEMBL29357283 | 0.88 | GCK (0.52) | MEN1KMT2ANPC1CASP3RAB9A | |
| SCHEMBL21395074 | 0.86 | CYP3A4 (0.53) | MEN1KMT2ANPC1CASP3RAB9A | |
| SCHEMBL21394759 | 0.86 | MEN1 (0.53) | MEN1KMT2ANPC1CASP3RAB9A | |
| SCHEMBL29354520 | 0.86 | MEN1 (0.53) | MEN1KMT2ANPC1CASP3RAB9A | |
| SCHEMBL21394480 | 0.81 | MAPT (0.44) | RAB9AMAOBCREBBPDEGS1NTRK1 | |
| SCHEMBL29357606 | 0.81 | MAPT (0.44) | RAB9AMAOBCREBBPDEGS1NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |