Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | F10 | P00742 | 8/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22479547 | 0.94 | ALDH1A1 (0.50) | ALDH1A1LMNAP4HTMF10POLB | |
| SCHEMBL21395090 | 0.90 | ALDH1A1 (0.51) | ALDH1A1LMNAP4HTMF10POLB | |
| SCHEMBL21384159 | 0.89 | ALDH1A1 (0.47) | ALDH1A1LMNAP4HTMF10HDAC3 | |
| SCHEMBL21394644 | 0.88 | ALDH1A1 (0.47) | ALDH1A1LMNAF10MEN1KMT2A | |
| SCHEMBL29358525 | 0.86 | ALDH1A1 (0.47) | ALDH1A1LMNAP4HTMF10HDAC3 | |
| SCHEMBL21394767 | 0.86 | ALDH1A1 (0.47) | ALDH1A1LMNAP4HTMF10HDAC3 | |
| SCHEMBL21394702 | 0.86 | MAOB (0.44) | ALDH1A1MAOAMAOBF10POLB | |
| SCHEMBL21394700 | 0.84 | ALDH1A1 (0.46) | ALDH1A1LMNAF10MEN1KMT2A | |
| SCHEMBL21394466 | 0.84 | ALDH1A1 (0.48) | ALDH1A1LMNAP4HTMF10HDAC3 | |
| SCHEMBL29356935 | 0.84 | ALDH1A1 (0.48) | ALDH1A1LMNAP4HTMF10HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |