Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 2/20 | 0.40 |
| ▸ | GCK | P35557 | 6/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.37 |
| ▸ | RARA | P10276 | 2/20 | 0.36 |
| ▸ | RARB | P10826 | 2/20 | 0.36 |
| ▸ | RARG | P13631 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21395018 | 0.92 | FSCN1 (0.41) | EP300GCKCREBBPDEGS1RARA | |
| SCHEMBL21384385 | 0.92 | CREBBP (0.42) | GCKCREBBPDEGS1RARARARB | |
| SCHEMBL29358634 | 0.92 | CREBBP (0.42) | GCKCREBBPDEGS1RARARARB | |
| SCHEMBL21395001 | 0.87 | RAB9A (0.41) | CREBBPDEGS1F10NTRK1KDM4E | |
| SCHEMBL21394652 | 0.86 | F10 (0.40) | CREBBPDEGS1F10RXFP1 | |
| SCHEMBL21394480 | 0.86 | MAPT (0.44) | GCKCREBBPDEGS1RARARARB | |
| SCHEMBL29357606 | 0.86 | MAPT (0.44) | GCKCREBBPDEGS1RARARARB | |
| SCHEMBL21395054 | 0.85 | GCK (0.41) | GCKDEGS1RARGKDM4E | |
| SCHEMBL29358537 | 0.85 | GCK (0.41) | GCKDEGS1RARGKDM4E | |
| SCHEMBL21394784 | 0.85 | GCK (0.44) | GCKCREBBPDEGS1RARGF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |