Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 3/20 | 0.38 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29353798 | 0.85 | SCD (0.52) | RAB9AMAPTALDH1A1KMT2ASCD | |
| SCHEMBL21394882 | 0.85 | SCD (0.52) | RAB9AMAPTALDH1A1KMT2ASCD | |
| SCHEMBL21394491 | 0.85 | RAB9A (0.43) | RAB9AMAPTALDH1A1KMT2ASCD | |
| SCHEMBL21394922 | 0.82 | RAB9A (0.55) | RAB9AMAPTALDH1A1KMT2ASCD | |
| SCHEMBL29357533 | 0.82 | RAB9A (0.55) | RAB9AMAPTALDH1A1KMT2ASCD | |
| SCHEMBL21395006 | 0.82 | MEN1 (0.52) | RAB9AMAPTALDH1A1KMT2AFFAR1 | |
| SCHEMBL29356723 | 0.80 | ALDH1A1 (0.47) | RAB9AMAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL21394836 | 0.80 | ALDH1A1 (0.47) | RAB9AMAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL21394887 | 0.80 | MAPT (0.47) | RAB9AMAPTALDH1A1KMT2ASCD | |
| SCHEMBL21394591 | 0.80 | RAB9A (0.45) | RAB9AMAPTALDH1A1KMT2AFSCN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |