Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 13/20 | 0.46 |
| ▸ | TTR | P02766 | 3/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1564729 | 0.93 | MET (0.48) | METTTRAPPLMNAMAPT | |
| SCHEMBL1564188 | 0.89 | MET (0.52) | METTTRAPPCA12CA4 | |
| SCHEMBL2135997 | 0.88 | MET (0.42) | METTTRAPPLMNAMAPT | |
| SCHEMBL2140473 | 0.88 | MET (0.42) | METTTRAPPLMNAMAPT | |
| SCHEMBL2140613 | 0.88 | MET (0.42) | METTTRAPPLMNAMAPT | |
| SCHEMBL1563937 | 0.88 | MET (0.47) | METTTRAPPLMNAMAPT | |
| SCHEMBL1565168 | 0.87 | MET (0.46) | METTTRAPPLMNAMAPT | |
| SCHEMBL2138389 | 0.86 | MET (0.45) | METTTRAPPLMNAMAPT | |
| SCHEMBL1565022 | 0.86 | MET (0.45) | METTTRAPPCA12CA4 | |
| SCHEMBL1564125 | 0.83 | MET (0.55) | METTTRAPPCA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110065859-A1 | THERMALLY STABLE ALIGNMENT MATERIALS | ROLIC AG (CH) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065859-A1 | THERMALLY STABLE ALIGNMENT MATERIALS | PARG, PARN, PUF60 | MET 4377/4885TTR 3725/4885APP 3392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.