Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 9/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.42 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1564277 | 0.93 | MET (0.44) | METALOX5TTRLMNAMAPT | |
| SCHEMBL1564228 | 0.89 | MET (0.48) | METALOX5TTRAPPCA12 | |
| SCHEMBL3629059 | 0.89 | MET (0.48) | METALOX5TTRAPPCA12 | |
| SCHEMBL1565264 | 0.89 | ALOX5 (0.45) | METALOX5TTRLMNAMAPT | |
| SCHEMBL2137177 | 0.89 | MET (0.37) | METALOX5LMNAMAPTAPP | |
| SCHEMBL679370 | 0.89 | MET (0.37) | METALOX5LMNAMAPTAPP | |
| SCHEMBL2139564 | 0.88 | MET (0.46) | METALOX5TTRLMNAMAPT | |
| SCHEMBL1565064 | 0.88 | MET (0.42) | METALOX5TTRLMNAMAPT | |
| SCHEMBL1563983 | 0.87 | MET (0.42) | METALOX5TTRLMNAMAPT | |
| SCHEMBL2142251 | 0.87 | MET (0.42) | METALOX5TTRLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110065859-A1 | THERMALLY STABLE ALIGNMENT MATERIALS | ROLIC AG (CH) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065859-A1 | THERMALLY STABLE ALIGNMENT MATERIALS | PARG, PARN, PUF60 | MET 4377/4885ALOX5 2934/4885TTR 3725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.