Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MPO | P05164 | 4/20 | 0.52 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3558008 | 0.91 | MPO (0.56) | HTTSMN1; SMN2MPOS1PR1CYP2C19 | |
| SCHEMBL15322279 | 0.84 | HTT (0.57) | HTTSMN1; SMN2MPOS1PR1PARP1 | |
| SCHEMBL5058656 | 0.84 | ALDH1A1 (0.45) | HTTSMN1; SMN2MPOS1PR1HPGD | |
| SCHEMBL24961607 | 0.83 | HTT (0.50) | HTTSMN1; SMN2MPOS1PR1HPGD | |
| SCHEMBL30873950 | 0.82 | MPO (0.76) | HTTSMN1; SMN2MPOS1PR1PARP1 | |
| SCHEMBL21396194 | 0.82 | MPO (0.76) | HTTSMN1; SMN2MPOS1PR1PARP1 | |
| SCHEMBL18509269 | 0.82 | HTR2A (0.63) | HTTSMN1; SMN2MPOS1PR1PARP1 | |
| SCHEMBL10678420 | 0.82 | HTR2A (0.63) | HTTSMN1; SMN2MPOS1PR1PARP1 | |
| SCHEMBL19872704 | 0.82 | MPO (0.56) | HTTSMN1; SMN2MPOS1PR1PARP1 | |
| SCHEMBL4797310 | 0.81 | DYRK1A (0.47) | HTTSMN1; SMN2MPODYRK1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183358-A2 | WHOLE CELL PROCESSES TO PRODUCE NITROAROMATICS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2019-09-26 | — | — | WO | disclosed |